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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308cdff72627537485aee565027726c64f56e3b9778550a4c2d71fc0d3a36d53' 
  AND token = 'FLklj/7sJRV29bKbopM4nwzZqzOMeNFsdpqiMwoU8l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}