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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc564cb65643c25006d693140c85f0f011bd426967262dd0c9c5c8453089dc2' 
  AND token = 'wW0R5s3fuvzY+pCViAld2tDl0F+xHsPiKOrQ6qIIrLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}