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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c777f85ae8753301770dc737c03964e376394e24ac7e368fcaca03b3fec8f3a' 
  AND token = 'RRXkczgR3YP832oBt2TbMtx/T+UbdqAM3DPpHb3HkrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}