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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c0dc8d16ee36b86fc5423d9136b3b7730bd3827b5ab919391e075e7fa8fa5d' 
  AND token = 'JNfReFaPZj5k9wOfFXX7fyIyO7ITAn0+7rwrE8K7eBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}