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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c3c6643f13552e3bfb142e518794d4b406551a9fca2c42354bd3793badda6e' 
  AND token = 'CqxRQ9G1bjWA1/S/26o4oQkrRQKG/kz2BcoSuRdLYfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}