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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa48d738bc6c0d1bdc53fe644e4b70ae7e0cc229a1e654726b5fa1feec236d86' 
  AND token = 'p35Gg49UeGefU5oRVurymdLqn7ixPPMsH4WRKr8MF7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}