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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e3c4fa79b4f683d89d3e9892ba307e34e34dc2c47be63ee555c90b5496e3d7' 
  AND token = 'kIyTkF8hcHg5EkCd6l6yhH3SiAir5D5BSJwerTjWCTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}