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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b00c7a1f1256033c622114b13263d47f3b8efb94b7278ce5a51c5df3f957133' 
  AND token = 'qFV2ZSXsyPoAOAlLZg6hk11lx0eiGeo8Gb5LEAEtjlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}