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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488f97e9cd25be48d9ae62eec5ef1ee6395cbbb519d959c67df14e0a3da35ff4' 
  AND token = 'tomY1NTNvULcTCUg8fj+4CrQhuyOxJNwIIl5YcCxQi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}