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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72164dc55f3f7f2ca9db59aaf2d53c20addb2548e61b088ce356f88949a627a8' 
  AND token = '95cGONpzDhVNrDqp9Kto/bZ/1omM42LMQF54BQOlAbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}