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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca2b31095e7aa81bf6b29a37e06e40dd9a37f4cce3abb2883d9a1e4778a58fa' 
  AND token = '/wbZoMjUKj638Qg7af/38qan5jUAmRgYxLJkp+KN+eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}