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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df24bcdad3704008a80453179f55bb90c45c6d9a274bb92a1127dffb8f95d692' 
  AND token = '6po3wC5uVwb5V+VHK1doTG2TLoKX8Z1roC3IOzrqCHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}