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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32e3c7ed5813389eb8db7ed7572323145e0da505b2a929b4697d9cfe5b03985' 
  AND token = 'I5P1ena+Iq2fiu1Rz2Oz9VJjIwJMe9A0pUwoiWlJ8Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}