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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657b0b521f44a0f3648fb2abf1dd39d2b0dbe69119f4724d2151fb0c06420bd5' 
  AND token = 'PRuwXgJlUV/1a8fWR28SEzIsz1WwsEYI1R1cw6CjzPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}