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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a932466ab6aa2d084e6e2e1e6eb157086526d43df354716a90104754801e221f' 
  AND token = 'KxaQqDJ5CcY+6uxzKeCeesqcb/QO/W9b+KJBJEMEOuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}