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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b46f2f510b5046dff8b4149ad69de64fba4b19c645c7fae1cfc9d29aeda8cf0' 
  AND token = 'T2jdIDWqvEvei89+iOjriT/b7UFYfdMYxsT55JInt+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}