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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8919f45a2b2352bb330ff84e79f5972a4d7b67eb8e5a0bfb0450d55aaacb2c8d' 
  AND token = 'sl1jeisvEkhD/toWiaAW9/qp4o4aIfxmQ4D3mE8L5BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}