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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a7288329b344a8ba941603906c71da69980414cfd20194643c74f83713413c' 
  AND token = 'QejBS0QKK6cKO1Mi8WcFzVvruBq+ah90notG4QqH4UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}