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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e498e37e5fe83c13f8704e68575287d02fb0cc7cabb9d1d5bc06f6adb8845c' 
  AND token = '0gsS8ufpTt1Nj+IhC64czPHd0hKH9aZd1qG1fyBhj/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}