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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2f3290b74be503e39e594f28e8c3f46c10ef795841d71525ebb3335afdcad7' 
  AND token = '6f3zVNzB+cWdJxCWP1tHVTE9PmlaQIiRgynEqMZYWkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}