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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b099e04c16f2a93133ffd90fac30b402f104269fc671df19ef1c1dc1e76ee72' 
  AND token = 'Yen8nOPc74ciZ9nLPyPNJlgVSK2+l2yjOp82v8Iu7nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}