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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd81e93eb208d04433213a4f0f66b9635f52fff26fd379591328499b0c551d4' 
  AND token = '3/7f2oGV9L/FCJxI2e9d3CqdVm/Yty7hoO3JQaUcz9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}