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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837ef8fe417b6e89eacc0372972efc078bdf8ebb814aee8114a2b45c60761ed4' 
  AND token = 'fm+t9UnHBLB9IJKNV1wmB7E/1nT5sTaR06hPeJwDOcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}