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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e005a9b06b66dbbdf1ff141c78edf4b1fb46bca148df0a49ea50dd8b45289bde' 
  AND token = 'Z3989LYEj2Se5grN3zS5e3XAjh9jrir84maA8AbRS0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}