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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3fd24b8846819dec0a53c5c5ff2fe8bab64659f5440fda3b7c4d942f7c10be' 
  AND token = 'TzDnpYwm3EBFe7kd1mJniDN+oRAqUqfRncql5IUiCfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}