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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14e38e7f3d42b5357de21588d80d8ce1ad08822304e7c44b30f3e0c2d1b1285' 
  AND token = 'U/2/LtH/r8GXWd772tvE20S56g+uKBC54NceBMWSojQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}