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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227fc127c1f3a60c801b64acc2420661612278ca78e67a054c08d4427e65f33f' 
  AND token = 'wGAOHe05rMHCyR9JxbnUIeBh2+JNNfuP/1W3Mmk+azg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}