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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1452c48534b300f5ad994d6f726153be25f862d989fde26d885e67a7a1c2023' 
  AND token = 'TXz/3q5ydXCNgSIS+yvCRYcKcE/K5RiEaT9+7rMGBy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}