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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2a3b48446e07269a30a15bdb4eb8673f0a83f1a2843a2eeae2a9f8c55f19c6' 
  AND token = '+rKG7B4OhwkHok0+agYQeXlZGRCFeixmDkgsbmLf4Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}