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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cff60e6c9a18e54940f5181ffc4e45e08714a948a1c2837635d7f85c2bc2e9' 
  AND token = 'GKdD5rNHfQJEe2gDEH9wDm2HM9OupTD6dMVS7KkdAoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}