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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a8ec9dbc80f89e7c0f03c5040ed485480c246061c57fe35ce6a355a77d72f5' 
  AND token = '42ftGmpFSAe3/IfeCkpIXiBZzyvuh+hBykJpwUQTq0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}