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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fce7429b365e4bd069407876fda37caccdfe31dc98569a9cac64665aa015e4' 
  AND token = 'vPPPZIO8QGRFNHmGSx58d6w+OgdZAwWKksZ4mw7y5kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}