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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc41af8cf9f2e642170c12409da5b9e44388710894163f0e667eb88539260a3f' 
  AND token = 'vGwkQKXGKG5LooUMvE62rokt0INM2456zARl4uSWFAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}