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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a65a4937030f0e45b4c836700f04139e7c8b3666b9e4515520156110c0f839ff' 
  AND token = 'D0FuuNmiKV0K/ELlBeKrMgqJ95TcROqpUlsrypVJ4io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}