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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3570472e712bfe9c5c3cc7974e603811e761ab17aa7d0a2eaf04fdbc5166602' 
  AND token = 'EyxmE9iaI/iu7ZOuqbm6Gs7tzuNVy1pLTKbDCQ5zS0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}