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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cdf1422e97cb1f8afa5c3c5f6df2e22178446026533b0bbddc1e079e8ffdc8' 
  AND token = 'kb70Gz5hcOycROMi8QxZUGOd1KF0qRdQMZ7TX9CiTSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}