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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc980225cc82abcd60b8e4cdb0b368f3114a6e562bda73a6d7b6e0c041f5097' 
  AND token = 'ya58X8Ktw1e1Puh+SRHSpVrg8c2+9NRhBiRNkH1ZYZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}