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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4da5d4d5c62df3340886e1ec8d4e7d9b53e5a9d7468b8de729bc18c7b63cf567' 
  AND token = '48+mmM7CpV4TzmCZHHkgXBzlbbve3hA+MhEDuYJTDC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}