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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f2352e2c50573caf1b1a00168c7d1b049a61f8911ad3df6d70907b9f6fbeac' 
  AND token = '2jE/kEMOZDXZJ24P+K6XBogjwvEYDbC8RmE1yK3g0ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}