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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf375330e7ca1462d794d03f1e91af391bfe9c2757250acf517c979ef5d10a3a' 
  AND token = 'yodytm0yCqUPCLYSWp93t7vOx5iDgGEF+0BzP4FoMJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}