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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f1caeaab758f4be16e96a81e7d43dfcdd679b9cc4a63d2a0fd8ff34846c022' 
  AND token = 'VIXCrsjBNGBTb07Q/5R76g57yG/NaRVKFnI1ciUcVWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}