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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b2648e5a9bdb6f678b6d146571cf2ab150c5cfd4c70d2adce8a1ef7209d797' 
  AND token = '/jmYgMQK1U4va7cXmwsW7fc2VZfaogRKbQGEG5BfoNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}