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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf00643f73cf171785190f3e8ec98b5df13d717270b3bc81381e0b0e30df31c7' 
  AND token = 't6Np1HYDnTKM7m3Tb1lkhGhCYV8Dpz5LCt+asQ0+I+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}