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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9347449c7abfa02dbe7c40f20c3d3f57cc4732513ebf7ac5d3503431c43cdb9f' 
  AND token = '8YqM4FMmDLJssy17YQMTs+2HLwp3zWyTrjxtj0puMhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}