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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f595c14798c2f765b0fd1100c345b9e67f381e6b5c9fc3860837581b68972bb1' 
  AND token = '9GlJfZC21SyovVDvcTtydcViICj7txf6dRWItdLu6CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}