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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4f800caf73239b693118d12e089bce643aca2e0ef47ae048ff71f07ff0e0b2' 
  AND token = 'eDJTj50idGjaxUtyrfijNhF7plc5U2lAG5myJP3X2bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}