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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21486d25d7d027bb83fb20890586c51888c38c28606435f2aa8ff300dd0b1a20' 
  AND token = 'NJlQZ5xtq4giz50rIPz7ULE6mJdnMh1RwkCtshoA2C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}