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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b95b1989f6b758dfa376e387a63ac1cd5583f5fa4c93cd1b0372f733650001' 
  AND token = '8vRvv/VykyEsA4bIsCc0oZrqYV0GR8t+IAF5vwTzD64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}