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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88fde7da53e378545eef65d41e3b5766b822c4b24d54ea87fa2c6dc36499a54' 
  AND token = 'yxsR1VvPfTtnB18qmB8VJrWu0QfHDv6DhW9jScaChXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}