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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8b1879eea1e2131f7f74e0a07f203687c584ef6550ef7009244b7ef3f5fcfa' 
  AND token = 'CEHgcKgswgo7ZelRhG0UvmJUliJz1RlTBH9g+Use9mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}